Re: [Freesurfer] GLM in groups with unequal size

Hi Eelco

it isn't really a question of whether our implementation is senstitive to this. It's that in general your power will be constrained by the size of the smaller group (I assume this is Type 2 diabetes by the way).

cheers Bruce

On Thu, 13 Oct 2016, Eelco van Duinkerken wrote:

Hi all, I am using FS with data from 2 different studies that were acquired on the same MRI-machine with the same T1 and FLAIR sequences. Unfortunately, the group sizes are not very balanced, with 31 controls, 16 obese and 32 diabetes patients.

Is the GLM for thickness used in FS very sensitive to this unequal group size?

Thanks for the help,

Eelco