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Hello,
I have done freesurfer (v6) longitudinal preprocessing for 20 subjects (baseline and 2-year follow-up). We also have levels of some blood biomarkers (e.g. tau, neurofilament light) for these subjects at the baseline. I am interested to figure out if the level of blood biomarkers at the baseline is related to the amount of cortical thinning over time, and if so, which brain regions’ cortical thinning are significantly correlated with the blood biomarker. I was wondering if you could please guide me through this analysis and let me know how I can do it.
Thanks Best, Foad