what is the main volume you are trying to save? If it's not "conformed" (i.e. 256^3 and 1mm isotropic, 8 bits/voxel) tkmedit probably isn't the right tool. In this case, try using freeview
Bruce
On Wed, 12 Oct 2011, Wei-Ta Chen wrote:
Hi: When I finish white matter editing and try to save the edited main volume by "Save Main Volume" of the "File" menu on TKMedit Tools window, there is a dialogue asking me:"Are ou sure you wish to save the changes to the main volume". When I clicked yes, error message appeared as follows:" Error. Couldnt save volume. This session was started in read-only mode. you cannot save changes." I changed my file permission to 777 (but I forgot to check my original permission settings) and saved again but in vain. Why was this error message? What should I do for now to avoid losing the edited WM results? Thanks for your help. Best, Wei-Ta Chen