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Freesurfer experts,
I have two questions that probably show my lack of understanding of many things related to thickness comparisons.
I have a group of controls and a single subject with pathology. I'd like to run a thickness analysis comparing them. I realize this is not ideal from a statistical standpoint, but due to the rarity of the disease, we'd like to see the results anyways.
Currently I'm using mri_glmfit followed by mri_fdr to do this comparison.
My questions are:
1) Is this FDR tool robust enough to handle this type of one-vs-many analysis? Is there a better way?
2) Generally, for one-vs-many analyses, I'd like to use a z-score. Is there a good way to convert this -log10(p) value from sig.mgh into a threshold for z.mgh instead? The dumb thing of back converting from p-value to z-score doesn't give the same maps once thresholded (there is probably an obvious reason for this that I'm missing).
thank you for any help you can provide!
quentin funk
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