Hi Alessandra
it's really an empirical question. If 1 image has sufficient SNR/CNR, then adding a second doesn't always help (as it induces some blurring due to interpolation). But if your single image is noisy, which it might be at 0.8 iso, then a second will help. You might try it on one or two subjects and see what you think. An alternative, if you are not already getting them, would be a T2-space or FLAIR T2-space, which can help avoid dura and such
cheers Bruce
On Wed, 7 Mar 2018, Alessandra Macbeth wrote:
Hi there, I know in the past, it was recommended to acquire 2 T1 scans so that they could be averaged for better SNR, etc. in order to improve cortical thickness and surface area measurements. Is this still the recommendation? We have a few extra minutes in our scanning protocol and are debating whether to include a 2nd T1.
Our parameters are: MPRAGE with .8mm^3 voxel size, slice thickness of .8, FA = 8 degrees, TR = 2400ms, TE = 2.72ms, TI = 1060ms.
Best, Alessandra
-- Alessandra Macbeth, M.A. Doctoral Candidate - Department of PsychologyUniversity of California, Riverside