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Hello Antonio, With the 7.4.1 release, you can install R2014b or R2019b matlab runtime environment into the freesurfer tree. Earlier freesurfer releases use R2014b. I would setup the freesurfer environment first, and then pass in the value of FREESURFER_HOME on the command line as listed below. Below, I have shown using R2019b with a linux install of Freesurfer 7.4.1 using bash shell. - R. - - - - - $ export FREESURFER_HOME=/usr/local/freesurfer/7.4.1 <--- linux install path $ source $FREESURFER_HOME/SetUpFreeSurfer.sh <... output deleted ... showing SUBJECTS_DIR and other environment variables> $ cd $FREESURFER_HOME/bin $ sudo FREESURFER_HOME=$FREESURFER_HOME ./fs_install_mcr R2019b I believe this sets things up (for R2019b) so the libmwm* libraries are installed under $FREESURFER_HOME/MCRv97/bin/glnxa64. You can try adding that path (or any path the fs_install_mcr script output recommends) to the start of LD_LIBRARY_PATH. You should remove any other entries to a different MATLAB distribution other than the one you actually install. On May 9, 2024, at 12:45, Antonio Di Renzo <antoniomp777@hotmail.it> wrote: External Email - Use Caution Messers FreeSurfer developers,I dowloaded MCR zip file for linux in /home/vboxuser/Downloads from MatLab website.I extracted files in new foldern named Matlab_Component_Runtime_R2014b in Downloads.I am trying to install Matlab Component Runtime, but the the following command: fs_install_mcr R2014b does not work.Where can I find the right step by step MCR installation guide?Thank you,Antonio_______________________________________________Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer