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Hello Freesurfer, Currently, I am using the Petsurfer manual, which is easily understandable and clear. Nonetheless, I have a question regarding the "mri_glmfit" step. As far as I know, this command is used to correct data for multiple comparisons among all the ROIs in the aparc+aseg.mgz file. Can you please confirm if my understanding is correct?
mri_glmfit.bin --y lh.all.suvr.sm05.proj0.5.nii.gz --fsgd 2G0C.fsgd --C patients_vs_controls.mtx --surf fsaverage lh --cortex --glmdir lh.patinets_vs_controls
In particular, I am interested in correcting data across lobes instead of across all ROIs. I followed the steps mentioned in the FS forum to create lobes, and I can observe lobe annotations in the wmparc.mgz file. I am curious to know whether using the "--annot" flag will adjust the p-values across different lobe ROIs instead of all ROIs in the aparc+aseg.mgz file. I have attempted this, but it appears to only change the name of the annotation in the final statistics file, and the p-value remains the same. Do I need to include any additional arguments in the command?
Thanks for your help John