Hi everyone,
I am trying to extract regional cortical thickness but confused with the altered values for the same subject within two days.
In our experiment, participants were scanned with the identical protocol in three times continuously: including baseline, 2 hours, 24 hours later. All T1s were processed by FS 5.3 and further normalized into fsaverage space, as well as a customized ROI. Interestingly, both of the regional CT and average CT of whole brain showed impressive variance among three timepoints for the same subjects. Moreover, if the T1 in the second and the third scan was coregister to the baseline scan and rerun the pipeline, the values is not very convincing. I wonder this variance was caused by the different head position in the scanner. Is there any suggestion to get rid of that? Which cortical thickness value could be trust most in my case? Any comments is appreciated. Thank you in advance.
Here is one example from my test. Subject regional CT average CT of whole brain bu45_t1 2.49833562 2.18242687 bu45_t2 2.540465325 2.233703478 bu45_t3 2.63002383 2.202483542 bu45_t2_to_t1 2.636101336 2.237099006 bu45_t3_to_t1 2.499173829 2.216584361
All the best Meng