Dear Kim,
This may be of interest to you:
http://dx.plos.org/10.1371/journal.pone.0038234
Cheers, Ed
On 24 Mar, 2014, at 17:00, freesurfer-request@nmr.mgh.harvard.edu wrote:
Message: 3 Date: Mon, 24 Mar 2014 12:28:29 +0900 From: jh kim jhkim.merrf@gmail.com Subject: Re: [Freesurfer] Difference in volumes btw 5.1 and 5,3 To: Freesurfer support list freesurfer@nmr.mgh.harvard.edu Message-ID: <CADiwdtbtNUbiXaaQgoR9bwLBrEwFDfu4 +Zv5VhViDhz3nfQOCg@mail.gmail.com> Content-Type: text/plain; charset="iso-8859-1"
Dear Prof. Fischl
Thanks for the valuable comments.
Kim
2014-03-23 3:26 GMT+09:00 Bruce Fischl fischl@nmr.mgh.harvard.edu:
Hi Kim
we of course always strive to make things more accurate, but in the end it will depend on the details of your acquisition and such. I don't think I have a better answer than that, other than to say look at the segmentations and see if you think they are more accurate in one case than the other.
sorry Bruce On Sun, 23 Mar 2014, jh kim wrote:
Dear Prof. Fischl Thanks for the prompt response.
The more specific reason of my query is that there was a difference in statistical significance between two FS versions. For example, the result of group comparison of left thalamic volumes
(ANCOVA
controlling for age and eICV) is statistically significant (p = 0.04)
when
using FS 5.1, whereas the result is no longer significant at all (p =
0.28)
in case of FS 5.3. I'm a little confused about this discrepancy. Which result should I trust?
Thank you in advance for your comments.
Kim
2014-03-23 2:59 GMT+09:00 Bruce Fischl fischl@nmr.mgh.harvard.edu: Hi Kim
there are probably lots of little reasons for the differences. This is always true for different versions, and the reason we nevermix versions
cheers Bruce On Sun, 23 Mar 2014, jh kim wrote:Dear FS lists When I measured subcortical GM volumes in the same subjects by
using bothversion 5.1 and 5.3, I have observed a considerable difference
in volumesbetween the two versions. For instance, please see the left thalamic volumes below. I cannot figure out why there is much difference between the
versions.Which result is more reliable?
Left-Thalamus-Proper_5.3 Left-Thalamus-Proper_5.1 10313 9757 8924.8 7746 9834.8 8287 7935.2 7034 8764.1 7747 9411.8 8037 7636.7 8051 9334.7 8255 10024.3 8171 8757.7 6900 9540.9 8316 9294.4 8369 8091 7366 9103.7 7818 9310.2 7974 7583 6872 9838.9 8911 8829.6 8004 9094.8 6973 9492.3 8922 8821.6 7691 7971.6 7376 9901.2 8936 9773.9 8855 9283.7 7615 8801.6 7690 8505.1 7325 8981 7258 9644.7 8860 9104.2 8298 8494.8 7402 9024.9 7721 8117.8 7226 8001.8 7548 8392.3 7668 8606.6 8173 9126.7 7595 8093 7885 8317.7 7157 10556 9307 8669.6 8374 8034.7 7338 8148.5 7276 9048.1 8064 8160.1 7014 8747.9 7894 8329.9 6866 8415.8 8189 9246.9 8256 8194.1 7183 9629.2 9579 7688.2 6398 8349.2 8238 8366.2 7348 8436.5 7616 8372.3 6977 9396.4 7589 9327.5 7684 10001.8 8627 9762.4 9228 8841 8532 8342.4 8024 8645.7 7725
Any comment would be appreciated. Thank you.
Kim
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