Hard to say for sure, but I would guess you have an incorrectly fixed topological defect in that region.

Cheers Bruce

From: freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu On Behalf Of Edoardo Pinzuti Sent: Wednesday, October 28, 2020 7:02 AM To: Freesurfer support list freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] Problem with pial and white matter segmentation

External Email - Use Caution Dear Freesurfer team,

I am having trouble with the pial and white matter segmentation of one subject (you can see the picture attached), I tried to set control points but it did not work completely. The segmentation looks not good at all for some slices, do you know what I could do ?

Thanks

Edoardo