Bbregister is rigid by default (since it is within subject), so you would need a rigid/affine version of synthmorph

-----Original Message----- From: freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu On Behalf Of Hoffmann, Malte,PhD Sent: Friday, December 13, 2024 7:47 AM To: Freesurfer support list freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] synthmorph for functional registration?

We haven't explored this yet, but I'd be curious to know as well.

________________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu on behalf of Josh nimzodisaster@gmail.com Sent: Friday, December 13, 2024 00:12 To: Freesurfer support list Subject: [Freesurfer] synthmorph for functional registration?

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bbregister is known to be really could at registering functionals to T1w image. I am curious as to whether synthmorph performs close to bbregister or not when registering epi to the structural.

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