Thank you very much for your prompt response. However, I am doing the same analysis (with Repeated Measures ANOVA 2x2) in different MRI acquisitions, so I would like to do the same analysis in freesurfer.

Could you please help me?

Thank you,

Best regards,

Maria.

2016-02-18 23:22 GMT+01:00 Douglas N Greve greve@nmr.mgh.harvard.edu:

It will be much easier if you subtract time point 1 from 2 then do a two-group t-test. See https://surfer.nmr.mgh.harvard.edu/fswiki/PairedAnalysis

On 02/18/2016 05:37 AM, María Díez Cirarda wrote:

...

Dear FS experts,

I am trying to do a longitudinal analysis with a Repeated Measures ANOVA 2x2, with two groups (experimental and control group) and two times (pre and post treatment).

First, I have followed the Longitudinal Processing Tutorial:

1. I have 2 acquisitions per subject so, I created a subject template

(BASE) for each pair of subjects 2) I created the two longitudinal runs

Now I am confused, because I don´t know wether I have to:

1. do a Longitudinal QDEC table with two columns (time and group)

or 2) create a FSGD File, (or a DOSS file?) and create the contrasts.

If I have to create the FSGD file, Would this be OK?

GroupDescriptorFile 1 Class Subject 1 Class Subject 2 Variables Tp1vsTp2.Gr1Exp Tp1vsTp2.Gr2Control Input Subject1-tp1 Subject1 1 0 Input Subject1-tp2 Subject1 -1 0 Input Subject2-tp1 Subject2 0 1 Input Subject2-tp2 Subject2 0 -1

Contrasts: Mtx file: 0 0 1 0 0 0 0 -1 0 0 1 -1

Were do I have to create the FSGD file? In subjects folder or inside qdec folder? The group descriptor file must be "subject1" "subject2", or should I introduce the specific names of the folders from the subjects of my

study?

...

Thank you in advance,

Maria.

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