Hi Eli

it's hard to say without looking at an image. Can you upload a subject and point us at a spot you think is incorrect? And do you really think the thickness should be 0 - there is no gray matter left at all? That seems unlikely....

cheers Bruce

On Wed, 10 Jan 2018, Rockers, Elijah D. wrote:

Hello,

We have some images that reflect severe atrophy in some subjects, in which gray matter is virtually undetectable on the MRI in some regions. However, upon checking the segmentations visually, the white/pial surfaces are reflecting a significant cortical thickness in these areas.

Is there perhaps any recon-all setting that might extend the white matter area out a little more aggressively than it does with the default settings?

Thanks,

• Eli

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