Hello all,
I have been slowly processing a longitudinal dataset off and on again since last August, sourcing /usr/local/freesurfer/nmr-stable6-env. Does this represent v.6.0-beta or v.6.0 in development? We were initially interested in applying the hippocampal subfield segmentation functionality on (1mm) T1 MPRAGE acquisitions and have found varying reproducibility, and questionable segmentation, of certain scans. I was aware that these volumetric measurements were to be interpreted with caution, but I'm separately wondering if the data I have processed in this environment can be trusted in analysis of cortical thickness change or if reprocessing with a previous version would be advised.
-Brendan
----------------------------- Brendan P. Grafe MSc Clinical Research Assistant Berenson-Allen Center for Noninvasive Brain Stimulation Beth Israel Deaconess Medical Center 330 Brookline Avenue Boston, MA 02215 Tel: 617-667-0256 Fax: 617-975-5322
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It is not a matter of "trusting" it so much as it will not represent an actual version of freesurfer. beta versions should not be used for production analysis. I would reprocess with a previous version.
doug
On 02/18/2016 02:45 PM, Grafe,Brendan P. (BIDMC - Neurology) wrote:
Hello all,
I have been slowly processing a longitudinal dataset off and on again since last August, sourcing /usr/local/freesurfer/nmr-stable6-env. Does this represent v.6.0-beta or v.6.0 in development? We were initially interested in applying the hippocampal subfield segmentation functionality on (1mm) T1 MPRAGE acquisitions and have found varying reproducibility, and questionable segmentation, of certain scans. I was aware that these volumetric measurements were to be interpreted with caution, but I’m separately wondering if the data I have processed in this environment can be trusted in analysis of cortical thickness change or if reprocessing with a previous version would be advised.
-Brendan
Brendan P. Grafe MSc
Clinical Research Assistant
Berenson-Allen Center for Noninvasive Brain Stimulation
Beth Israel Deaconess Medical Center
330 Brookline Avenue
Boston, MA 02215
Tel: 617-667-0256
Fax: 617-975-5322
This message is intended for the use of the person(s) to whom it may be addressed. It may contain information that is privileged, confidential, or otherwise protected from disclosure under applicable law. If you are not the intended recipient, any dissemination, distribution, copying, or use of this information is prohibited. If you have received this message in error, please permanently delete it and immediately notify the sender. Thank you.
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Douglas N Greve -
Grafe,Brendan P. (BIDMC - Neurology)