Regarding: Comparing hippocampal volume from different scanners for two different population
Dear freesurfer experts,
I am presently trying to calculate hippocampal volume for two different study groups. One study group images (MDD) was acquired on 1.5T and the other age-matched study group (Healthy controls) on 3T MRI. On doing the statistics I have significant differences in the hippocampal volume correlating with their cognitive scores between the two study groups. Do I need to take into consideration different scanner parameters when doing the statistics? How do I go about it?
Thanks for your help.
Kind regards,
Sam
You do need to take it into account, but you cannot if one group is 1.5T and the other is 3T.
On 5/28/17 10:41 AM, Dr Sampada Sinha wrote:
Dear freesurfer experts,
I am presently trying to calculate hippocampal volume for two different study groups. One study group images (MDD) was acquired on 1.5T and the other age-matched study group (Healthy controls) on 3T MRI. On doing the statistics I have significant differences in the hippocampal volume correlating with their cognitive scores between the two study groups. Do I need to take into consideration different scanner parameters when doing the statistics? How do I go about it?
Thanks for your help.
Kind regards,
Sam
-- Dr Sampada Sinha Research medical scientist (B) Department of Geriatric Mental Health (DGMH) King George Medical University Lucknow-226003 , Uttar Pradesh India
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Thanks Dr Greve for your reply. I understand it can be taken into account if study group is the same and different scanner is used on the same group. So does it mean there is a differential change in volume depending on the field strength?
Appreciate your help.
Kind regards,
Sam
On Tuesday, May 30, 2017, Douglas Greve <greve@nmr.mgh.harvard.edu javascript:_e(%7B%7D,'cvml','greve@nmr.mgh.harvard.edu');> wrote:
You do need to take it into account, but you cannot if one group is 1.5T and the other is 3T.
On 5/28/17 10:41 AM, Dr Sampada Sinha wrote:
Dear freesurfer experts,
I am presently trying to calculate hippocampal volume for two different study groups. One study group images (MDD) was acquired on 1.5T and the other age-matched study group (Healthy controls) on 3T MRI. On doing the statistics I have significant differences in the hippocampal volume correlating with their cognitive scores between the two study groups. Do I need to take into consideration different scanner parameters when doing the statistics? How do I go about it?
Thanks for your help.
Kind regards,
Sam
-- Dr Sampada Sinha Research medical scientist (B) Department of Geriatric Mental Health (DGMH) King George Medical University Lucknow-226003 , Uttar Pradesh India
Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
there might be. The problem with having all one group from one scanner and all other other group from another scanner is that you cannot tell what is due to scanner and what is due to group.
On 05/30/2017 11:50 AM, Dr Sampada Sinha wrote:
Thanks Dr Greve for your reply. I understand it can be taken into account if study group is the same and different scanner is used on the same group. So does it mean there is a differential change in volume depending on the field strength?
Appreciate your help.
Kind regards,
Sam
On Tuesday, May 30, 2017, Douglas Greve <greve@nmr.mgh.harvard.edu javascript:_e(%7B%7D,'cvml','greve@nmr.mgh.harvard.edu');> wrote:
You do need to take it into account, but you cannot if one group is 1.5T and the other is 3T. On 5/28/17 10:41 AM, Dr Sampada Sinha wrote:Dear freesurfer experts, I am presently trying to calculate hippocampal volume for two different study groups. One study group images (MDD) was acquired on 1.5T and the other age-matched study group (Healthy controls) on 3T MRI. On doing the statistics I have significant differences in the hippocampal volume correlating with their cognitive scores between the two study groups. Do I need to take into consideration different scanner parameters when doing the statistics? How do I go about it? Thanks for your help. Kind regards, Sam -- Dr Sampada Sinha Research medical scientist (B) Department of Geriatric Mental Health (DGMH) King George Medical University Lucknow-226003 , Uttar Pradesh India */ /* _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>-- Dr Sampada Sinha Research medical scientist (B) Department of Geriatric Mental Health (DGMH) King George Medical University Lucknow-226003 , Uttar Pradesh India *//*
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