Dear Freesurfers,
I had a question about interpreting the results of the Monte-Carlo simulation. It is my understanding that the clusters are labeled based on the value of the maximum significant vertex in a cluster. So, assuming that a cluster kind of borders or extends over 2 adjacent regions, it could well be labeled as a single region whereas anatomically, it would actually be 2 separate regions. Are there any suggestions for an atlas that could help me make my inferences more meaningful? Sorry if this is a naive question, my knowledge of anatomic labelling is less than impressive :-)
Thanks Koushik
Hi Koushik, you are correct it will report the label that the max falls into and so the entire cluster can fall across multiple labels. But I'm not sure what you are asking. You're cluster effectively forms it's own label, and, given that your cluster is somewhat unique, I'm not sure what pre-defined label would satisfy you. No matter what the labeling scheme, you'll always end up with overlap. doug
On 06/04/2012 10:35 AM, Govindarajan, Koushik Athreya wrote:
Dear Freesurfers,
I had a question about interpreting the results of the Monte-Carlo simulation. It is my understanding that the clusters are labeled based on the value of the maximum significant vertex in a cluster. So, assuming that a cluster kind of borders or extends over 2 adjacent regions, it could well be labeled as a single region whereas anatomically, it would actually be 2 separate regions. Are there any suggestions for an atlas that could help me make my inferences more meaningful? Sorry if this is a naive question, my knowledge of anatomic labelling is less than impressive :-)Thanks Koushik
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Thanks Doug for the response. Yes, I do understand that there is going to be overlap. My question is, is there a way to identify all the overlapping regions. Say, if the overlap is between prominent labels like Precentral and superior frontal, even though the cluster label might say precentral, I would be able to say that it extends to superior frontal also. But if the overlap were to happen between regions that are much less distinguishable, then the inferences made about the extent of differences might not be complete.
Thanks again Regards Koushik
________________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu [freesurfer-bounces@nmr.mgh.harvard.edu] On Behalf Of Douglas N Greve [greve@nmr.mgh.harvard.edu] Sent: Monday, June 04, 2012 10:00 AM To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Anatomic Inferences
Hi Koushik, you are correct it will report the label that the max falls into and so the entire cluster can fall across multiple labels. But I'm not sure what you are asking. You're cluster effectively forms it's own label, and, given that your cluster is somewhat unique, I'm not sure what pre-defined label would satisfy you. No matter what the labeling scheme, you'll always end up with overlap. doug
On 06/04/2012 10:35 AM, Govindarajan, Koushik Athreya wrote:
Dear Freesurfers,
I had a question about interpreting the results of the Monte-Carlo simulation. It is my understanding that the clusters are labeled based on the value of the maximum significant vertex in a cluster. So, assuming that a cluster kind of borders or extends over 2 adjacent regions, it could well be labeled as a single region whereas anatomically, it would actually be 2 separate regions. Are there any suggestions for an atlas that could help me make my inferences more meaningful? Sorry if this is a naive question, my knowledge of anatomic labelling is less than impressive :-)Thanks Koushik
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-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Nothing that I can think of, other than to just load it up in tksurfer and see where the cluster falls. doug
On 06/04/2012 11:18 AM, Govindarajan, Koushik Athreya wrote:
Thanks Doug for the response. Yes, I do understand that there is going to be overlap. My question is, is there a way to identify all the overlapping regions. Say, if the overlap is between prominent labels like Precentral and superior frontal, even though the cluster label might say precentral, I would be able to say that it extends to superior frontal also. But if the overlap were to happen between regions that are much less distinguishable, then the inferences made about the extent of differences might not be complete.
Thanks again Regards Koushik
From: freesurfer-bounces@nmr.mgh.harvard.edu [freesurfer-bounces@nmr.mgh.harvard.edu] On Behalf Of Douglas N Greve [greve@nmr.mgh.harvard.edu] Sent: Monday, June 04, 2012 10:00 AM To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Anatomic Inferences
Hi Koushik, you are correct it will report the label that the max falls into and so the entire cluster can fall across multiple labels. But I'm not sure what you are asking. You're cluster effectively forms it's own label, and, given that your cluster is somewhat unique, I'm not sure what pre-defined label would satisfy you. No matter what the labeling scheme, you'll always end up with overlap. doug
On 06/04/2012 10:35 AM, Govindarajan, Koushik Athreya wrote:
Dear Freesurfers,
I had a question about interpreting the results of the Monte-Carlo simulation. It is my understanding that the clusters are labeled based on the value of the maximum significant vertex in a cluster. So, assuming that a cluster kind of borders or extends over 2 adjacent regions, it could well be labeled as a single region whereas anatomically, it would actually be 2 separate regions. Are there any suggestions for an atlas that could help me make my inferences more meaningful? Sorry if this is a naive question, my knowledge of anatomic labelling is less than impressive :-)Thanks Koushik
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
freesurfer@nmr.mgh.harvard.edu