Dear all,
I have heard that the FWE correction sometimes could be demanding and kill very subtle differences, overall for example in aging studies with normal people and narrow-age intervals, or young people, where changes are supposed to be not very big.
So, do you know when uncorrected results are justified or at least permitted instead of FWE? Any paper or information about this specific FWE disadvantages in aid of p<0,001 uncorrected results?
Thank you very much in advance
Daniel Ferreira
Generally, reviews and editors will not let you publish without correcting for multiple comparisons. You might get an exception with a rare patient population or something like that. I don't understand your second question. doug
On 06/04/2012 11:22 AM, Daniel Ferreira wrote:
Dear all,
I have heard that the FWE correction sometimes could be demanding and kill very subtle differences, overall for example in aging studies with normal people and narrow-age intervals, or young people, where changes are supposed to be not very big.
So, do you know when uncorrected results are justified or at least permitted instead of FWE? Any paper or information about this specific FWE disadvantages in aid of p<0,001 uncorrected results?
Thank you very much in advance
Daniel Ferreira
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freesurfer@nmr.mgh.harvard.edu
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Daniel Ferreira -
Douglas N Greve