Hello Freesurfer group, I have a general question about the Freesurfer pipeline when applied to fMRI BOLD scans. In general, with heavily atrophied or older individuals, would there be no necessary corrections to make for atrophy due to the non-linear surface inflation transformation that is applied to every individual subject? I ask, as I we have atrophied subjects in our dataset and want to make sure a BOLD signal is comparable between tissues and subjects. Thanks
No, there is nothing special you need to do. FSFAST will sample halfway between the white and pial surfaces which will be as good as you can get for atrophied brains. doug
On 11/11/13 11:47 AM, Mario Ortega wrote:
Hello Freesurfer group, I have a general question about the Freesurfer pipeline when applied to fMRI BOLD scans. In general, with heavily atrophied or older individuals, would there be no necessary corrections to make for atrophy due to the non-linear surface inflation transformation that is applied to every individual subject? I ask, as I we have atrophied subjects in our dataset and want to make sure a BOLD signal is comparable between tissues and subjects. Thanks
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Douglas Greve -
Mario Ortega