Hi Antonio

probably both Bruce On Wed, 19 Nov 2014, Antonio Algaze Beato wrote:

Thank you very much for your response.  Out of curiosity, does someone know why the ADNI protocol has an anisotropic voxel resolution?

I was wondering if it had to do with the increased SNR being more beneficial for accurate segmentation than the gain in resolution from a 1mm isotropic voxel... or, perhaps it is meant to speed things up and and cover the whole brain a bit quicker?

Cheers,

Antonio

On Wednesday, November 19, 2014, Antonio Algaze Beato antonio.algaze@upr.edu wrote: Dear group, I am new to FS and the ADNI protocol, thus my question: is it ok to have a slice thickness of 1.2 mm and in-plane resolution of 1.05 mm for cortical segmentation and brain volume analyses? This seems to be a sequence suggested on the FreeSurferWiki (I am using a GE750 3T).  Doesn't the anisotropic resolution introduce a bias?

Thanks a lot!

-- Antonio Algaze, PhDUniversity of Puerto Rico Physics, UPR-Bayamón Radiology, UPR-School of Medicine