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Hello PetSurfer Developers On the tutorial page, I do not understand this part: --km-hb 11 12 13 50 51 52 specifies the ROIs to use as the high-binding region if using MRTM2. This creates km.hb.tac.nii.gz with the value for the high-binding region for each time point. What exactly is a high-binding region and how do these inputs affect the rest of the estimation? If I do not know what the high binding regions for a tracer are, may I leave this blank? Thank you.
You should read up on the MRTM2. Basically, when you run MRTM1, it computes a separate k2 for each voxel eventhough the k2 should be the same across the entire brain (since it actually refers to the reference region). With MRTM2, you estimate the single k2 value from high binding regions.
On 3/26/19 12:50 PM, Shane Schofield wrote:
External Email - Use Caution
Hello PetSurfer Developers
On the tutorial page, I do not understand this part:
--km-hb 11 12 13 50 51 52 specifies the ROIs to use as the high-binding region if using MRTM2. This creates km.hb.tac.nii.gz with the value for the high-binding region for each time point.
What exactly is a high-binding region and how do these inputs affect the rest of the estimation? If I do not know what the high binding regions for a tracer are, may I leave this blank?
Thank you.
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freesurfer@nmr.mgh.harvard.edu
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Greve, Douglas N.,Ph.D. -
Shane Schofield