No, it was not a problem with negative thickness but an inaccuracy/inconsistency with the way the surfaces were computed. It is not something that is easy to notice (which is how it made it past our QA). I would re-run them. doug

On 03/08/2014 11:21 PM, Gregory Kirk wrote:

In the release notes for 5.3 i find

Stable release version 5.3.0 is a bug fix release to correct the problem with pial and white surface creation affecting thickness and area measures.

Is this only related to netative thickness values, which i have never found. I have 150 subjects * 3 timepoints that i ran

on a cluster with condor linux and freesurfer version 5.1 i myself inspected time point 1 and did analysis and did not

find any unusual problems. i am preparing to do a longitudinal analysis of all 3 timepoints and wondering if

i should reprocess and reinspect everything, considering the bug fix and improvements for longitudinal stream.

thanks

greg _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer