Dear experts,
We are currently developing a MRI protocol for a longitudinal study that will take over in the next 3 years using a Siemens Prisma 3T.
We are interested in structural changes within cortical and sub cortical regions, we will also be acquiring DTI and a FLAIR scans. I have seen that for HC subfields .6 mm iso T1 seems to be the gold standard.
Being a new user of freesurfer and trying to make an educated decision regarding our scanning parameters, I was wondering if you have any recommendations regarding the T1 parameters.
Thank you very much,
Annie
Hi Annie
getting to 0.6mm over the whole brain will be hard and probably not worth it IMO. You could copy either the HCP (0.7mm) or ABCD (0.8mm I think). If you are interested in subfields specifically people typically do somewhat anisotropic 2D scans (e.g. 1mm slices, 0.4mm in-plane) perpindicular to the long axis of the hippocampus. There is some debate over what kind of scans, but I think more people like T2 than T1.
cheers Bruce
On Mon, 8 May 2017, Annie Duchesne wrote:
Dear experts, We are currently developing a MRI protocol for a longitudinal study that will take over in the next 3 years using a Siemens Prisma 3T.
We are interested in structural changes within cortical and sub cortical regions, we will also be acquiring DTI and a FLAIR scans. I have seen that for HC subfields .6 mm iso T1 seems to be the gold standard.
Being a new user of freesurfer and trying to make an educated decision regarding our scanning parameters, I was wondering if you have any recommendations regarding the T1 parameters.
Thank you very much,
Annie
Thank for your prompt input! ________________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu [freesurfer-bounces@nmr.mgh.harvard.edu] on behalf of Bruce Fischl [fischl@nmr.mgh.harvard.edu] Sent: May-08-17 10:56 AM To: Freesurfer support list Subject: Re: [Freesurfer] submillimeter resolution
Hi Annie
getting to 0.6mm over the whole brain will be hard and probably not worth it IMO. You could copy either the HCP (0.7mm) or ABCD (0.8mm I think). If you are interested in subfields specifically people typically do somewhat anisotropic 2D scans (e.g. 1mm slices, 0.4mm in-plane) perpindicular to the long axis of the hippocampus. There is some debate over what kind of scans, but I think more people like T2 than T1.
cheers Bruce
On Mon, 8 May 2017, Annie Duchesne wrote:
Dear experts, We are currently developing a MRI protocol for a longitudinal study that will take over in the next 3 years using a Siemens Prisma 3T.
We are interested in structural changes within cortical and sub cortical regions, we will also be acquiring DTI and a FLAIR scans. I have seen that for HC subfields .6 mm iso T1 seems to be the gold standard.
Being a new user of freesurfer and trying to make an educated decision regarding our scanning parameters, I was wondering if you have any recommendations regarding the T1 parameters.
Thank you very much,
Annie
freesurfer@nmr.mgh.harvard.edu