Thank you very much!

I will try again following your directions and I'll let you know.

Best,

Pietro

2013/11/19 Louis Nicholas Vinke vinke@nmr.mgh.harvard.edu

Hi Pietro, I think you should try redoing the control points from scratch, but with fewer control points and sparser placement. Currently you have 198 control points tightly packed in only a couple regions. Furthermore, there is one control point at 128, 128, 128 which is right in the thalamus which should not be there, maybe an accidental click?

Take a look at the placement of the control points in the snapshots on this tutorial page: https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/ ControlPoints_freeview

If you compare the norm.mgz volumes before/after editing, you will notice the extreme hyper-intense wm (130+) in the temporal lobes after adding control points and rerunning. The norm.mgz is passed to mri_pretess to create the wm.mgz. You can see there is overlap between the hyper-intense voxels on the norm and the voxels not being included in the wm mask, which leads to major errors in the wm surface. -Louis

On Fri, 15 Nov 2013, pietro de rossi wrote:

Good morning Dr Vinke,

...

did you have the chance to take a look at the subject I uploaded a few days ago?

thanks again.

Kind regards,

Pietro

-- Pietro De Rossi, MD

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