External Email - Use Caution
Hello FreeSurfer experts,
In my case-control study, I have a dataset of 5 healthy controls (HCs) and one patient (PAT). I was wondering if there is any way to perform GLM for PAT > HCs on brain morphometry data.
When I tried to follow instructions from here: https://secure-web.cisco.com/1og9s8_rd4Lyx1NIwR7d0GRha020qNYi0MbIToxO7mZZ68u..., the mri_glm fit command gives me the following error:
Class Size and Means of each Continuous Variable
1 HC 5 24.2000 0.6000
2 Tumor 1 50.0000 1.0000
ERROR: Class Tumor has 1 members. With 2 variables and using DODS, you need at least 3 members
It seems at-least three subjects are required in the Tumor category - because I have age and sex covariates in my fsgd file.
I was wondering if there is any way to still perform the above GLM analysis or any other alternatives available to compare HCs vs one PAT.
Thanks!
External Email - Use Caution
Hi FS experts,
I was wondering if someone could help me get the following issue resolved.
Thanks.
---------- Forwarded message --------- From: Martin Juneja mj70481@gmail.com Date: Fri, Dec 8, 2023 at 11:03 AM Subject: Case-controls study ! To: Freesurfer support list freesurfer@nmr.mgh.harvard.edu
Hello FreeSurfer experts,
In my case-control study, I have a dataset of 5 healthy controls (HCs) and one patient (PAT). I was wondering if there is any way to perform GLM for PAT > HCs on brain morphometry data.
When I tried to follow instructions from here: https://secure-web.cisco.com/1aK-KNfU8HH_e-fpaIAGAkK_0d2hcDIl4JpjyDUomASQEQQ..., the mri_glm fit command gives me the following error:
Class Size and Means of each Continuous Variable
1 HC 5 24.2000 0.6000
2 Tumor 1 50.0000 1.0000
ERROR: Class Tumor has 1 members. With 2 variables and using DODS, you need at least 3 members
It seems at-least three subjects are required in the Tumor category - because I have age and sex covariates in my fsgd file.
I was wondering if there is any way to still perform the above GLM analysis or any other alternatives available to compare HCs vs one PAT.
Thanks!
Try using DOSS (--fsgd your.fsgd doss) instead of DODS (which is the default).
On 12/8/2023 12:03 PM, Martin Juneja wrote:
External Email - Use Caution
Hello FreeSurfer experts,
In my case-control study, I have a dataset of 5 healthy controls (HCs) and one patient (PAT). I was wondering if there is any way to perform GLM for PAT > HCs on brain morphometry data.
When I tried to follow instructions from here: *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis https://secure-web.cisco.com/1og9s8_rd4Lyx1NIwR7d0GRha020qNYi0MbIToxO7mZZ68u0-1Mqs2-nbpGVMe8z4QqGla-8tTv7UImDK5tHBH8VpWK0lmJo4NejFJBd1Lo4QLqd8RIC_S2rJZEoTQuLgZ85yECAm8PcZ5AgEXxuwBNvU1NpEpny1iM26ExZEKUZeYJA5POwSpMNbFCDiNaG3yKTTOz69SZ6JlqCG9LNRz1oqhI9QpjRhtIsh043XuY5Pa8hnoe9MElhlpjE0zHCFgO8Jx90FD5Apzz6F5alIZRoxUR2qV-qRvGz39xFjyHsv2mJZ-9ZRjsssKMs-b8zAPBM7qebGdnxa1mxGiJ00_w/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsTutorial%2FGroupAnalysis, the mri_glm fit command gives me the following error:
Class Size and Means of each Continuous Variable
1 HC524.2000 0.6000
2 Tumor150.0000 1.0000
ERROR: Class Tumor has 1 members. With 2 variables and using DODS, you need at least 3 members
It seems at-least three subjects are required in the Tumor category - because I have age and sex covariates in my fsgd file.
I was wondering if there is any way to still perform the above GLM analysis or any other alternatives available to compare HCs vs one PAT.
Thanks!
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Martin Juneja