Hello,
I have an epilepsy patient brain that has an abnormality I'm not sure how to fix. I have attached a few screenshots to clarify my question. When comparing the left vs right mesial-temporal area, notice that the white matter surface line on the left encloses a lot of dark space and has a lot of artificial fills on the wm.mgz volume. This subject appears to have had a hippocampal resection. However, the segmentation classifies some of the dark space as hippocampus. While I understand that FS is based off of healthy, full brains, and that is why it has filled in the missing white matter (etc.) in that section, I am trying to decide on the best way to edit this brain.
Would you suggest deleting the artificial fills or leaving the brain as is? We are interested in both cortical and subcortical volumes.
Thanks for your input!
Lusineh
Hi Lusineh,
if you put the subject on our ftp site we'll take a look. I think there's probably a topology problem that is incorrectly fixed, but it's impossible to tell from a few slices.
cheers, Bruce On Fri, 6 Jun 2008, Lusineh Gharapetian wrote:
Hello,
I have an epilepsy patient brain that has an abnormality I'm not sure how to fix. I have attached a few screenshots to clarify my question. When comparing the left vs right mesial-temporal area, notice that the white matter surface line on the left encloses a lot of dark space and has a lot of artificial fills on the wm.mgz volume. This subject appears to have had a hippocampal resection. However, the segmentation classifies some of the dark space as hippocampus. While I understand that FS is based off of healthy, full brains, and that is why it has filled in the missing white matter (etc.) in that section, I am trying to decide on the best way to edit this brain.
Would you suggest deleting the artificial fills or leaving the brain as is? We are interested in both cortical and subcortical volumes.
Thanks for your input!
Lusineh
freesurfer@nmr.mgh.harvard.edu