Large discrepancy in left and right volumes of perirhinal/entorhinal cortices on FreeSurfer 7.1
External Email - Use Caution
Dear FreeSurfer developers,
Our research group used the FreeSurfer's recon-all tool to reconstruct 74 anatomical images from cognitively healthy older individuals and parcellate the cortex based on the Desikan-Killiany atlas. However, we are running into a consistent issue with the perirhinal volumes on the annot stats from BA_exvivo_thresh.stats, where there is a large discrepancy between the left and right hemispheres (larger left hemisphere). Upon visual and numerical investigation, it appears that this could be due to mis-labelling the right perirhinal vertices as entorhinal, resulting in an unusually small right perirhinal cortex, and unusually large right entorhinal cortex. Could you please clarify why this could be happening, and advise on next steps? We have used FreeSurfer 7.1 for this analysis.
Sincerely, Tulip Marawi
This e-mail is intended only for the named recipient(s) and may contain confidential, personal and/or health information (information which may be subject to legal restrictions on use, retention and/or disclosure). No waiver of confidence is intended by virtue of communication via the internet. Any review or distribution by anyone other than the person(s) for whom it was originally intended is strictly prohibited. If you have received this e-mail in error, please contact the sender and destroy all copies.
Do you see the same thing in the source BA data (in fsaverage)?
On 11/21/2023 10:22 AM, Marawi, Tulip wrote:
External Email - Use Caution
Dear FreeSurfer developers,
Our research group used the FreeSurfer’s recon-all tool to reconstruct 74 anatomical images from cognitively healthy older individuals and parcellate the cortex based on the Desikan-Killiany atlas.
However, we are running into a consistent issue with the perirhinal volumes on the annot stats from BA_exvivo_thresh.stats, where there is a large discrepancy between the left and right hemispheres (larger left hemisphere).
Upon visual and numerical investigation, it appears that this could be due to mis-labelling the right perirhinal vertices as entorhinal, resulting in an unusually small right perirhinal cortex, and unusually large right entorhinal cortex.
Could you please clarify why this could be happening, and advise on next steps?
We have used FreeSurfer 7.1 for this analysis.
Sincerely,
Tulip Marawi
*/This e-mail is intended only for the named recipient(s) and may contain confidential, personal and/or health information (information which may be subject to legal restrictions on use, retention and/or disclosure). No waiver of confidence is intended by virtue of communication via the internet. Any review or distribution by anyone other than the person(s) for whom it was originally intended is strictly prohibited. If you have received this e-mail in error, please contact the sender and destroy all copies./*
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
freesurfer@nmr.mgh.harvard.edu
-
Douglas N. Greve -
Marawi, Tulip