Sorry, caching is not possible with xhemi. You can just run the mris_preproc command multiple times, one for each subject, specifing a subject-specific output file for each. This is all  that the -qcache flag does anyway

On 11/08/2017 02:10 PM, Mehta, Chintan wrote:

Dear FreeSurfer Users,

I'm using FreeSurfer version 6.0. I've processing subjects with recon-all and performed surface-based interhemispheric registration (via Xhemi at https://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi).

I want to run a GLM on the subjects Area and Thickness from the differences (Left minus Right). When stacking subjects asymmetry maps, I wanted to use a "--cache-only".

The post at https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg27657.html seems to imply this requires running

...

recon-all -qcache -measure area -target fsaverage_sym -fwhm 10

-no-isrunning -s subjid -hemi lh for area at FWHM = 10.

This would create files with the left hemisphere area registered to fsaverage_sym at smoothing FWHM = 10: $subjid/surf/lh.area.fwhm10.fsaverage_sym.mgh

However, how do I do this also for the xhemi registration? I.e. create a file like $subjid/xhemi/surf/lh.area.fwhm10.fsaverage_sym.mgh

Then, if I do this, can I stack the subjects using something like:

...

mris_preproc --target fsaverage_sym --hemi lh

--xhemi --paired-diff \   --srcsurfreg fsaverage_sym.sphere.reg \   --cache-in area.fwhm10.fsaverage_sym \   --out lh.lh-rh.area.sm10.mgh \   --s subj1 --s subj2 ...

Thank you.

Best, Chintan

mris_preproc --target fsaverage_sym --hemi lh --xhemi --paired-diff \ --srcsurfreg fsaverage_sym.sphere.reg \ --meas thickness \ --out lh.lh-rh.thickness.sm00.mgh \ --s subj1 --s subj2 ...

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