Hi, I'm performing qdec. This my file.dat 1 diagnosis discrete 2 1 Pathology 2 Controls2 Thickness_lh continuous 03 Thickness_rh continuous 04 NPStest continuous 0 Continuous Factors: Mean: StdDev: ------------------- ----- ------- Thickness_lh 2.643 0.116 Thickness_rh 2.630 0.099 NPStest 0.774 1.203 Number of subjects: 31Number of factors: 4 (1 discrete, 3 continuous)Number of classes: 2Number of regressors: 8

NPStest is scored from 0 to 8.

Qdec produces this error:

Creating output directory /Applications/freesurfer/subjects/subject_prova/qdec/UntitledLoading y from /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/y.mghINFO: gd2mtx_method is dodsSaving design matrix to /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/Xg.datNormalized matrix condition is 1e+08Design matrix ------------------ 1.000 0.000 0.000 0.000 2.495 0.000; 1.000 0.000 0.000 0.000 2.712 0.000; 1.000 0.000 0.000 0.000 2.671 0.000; 1.000 0.000 0.000 0.000 2.728 0.000; 1.000 0.000 0.000 0.000 2.646 0.000; 1.000 0.000 0.000 0.000 2.555 0.000; 1.000 0.000 0.000 0.000 2.750 0.000; 1.000 0.000 0.000 0.000 2.555 0.000; 1.000 0.000 0.000 0.000 2.784 0.000; 1.000 0.000 0.000 0.000 2.586 0.000; 1.000 0.000 0.000 0.000 2.641 0.000; 1.000 0.000 0.000 0.000 2.561 0.000; 1.000 0.000 0.000 0.000 2.545 0.000; 1.000 0.000 0.000 0.000 2.495 0.000; 1.000 0.000 0.000 0.000 2.769 0.000; 1.000 0.000 0.000 0.000 2.740 0.000; 0.000 1.000 0.000 2.000 0.000 2.526; 0.000 1.000 0.000 2.000 0.000 2.761; 0.000 1.000 0.000 2.000 0.000 2.521; 0.000 1.000 0.000 0.000 0.000 2.592; 0.000 1.000 0.000 2.000 0.000 2.555; 0.000 1.000 0.000 2.000 0.000 2.671; 0.000 1.000 0.000 3.000 0.000 2.559; 0.000 1.000 0.000 3.000 0.000 2.469; 0.000 1.000 0.000 4.000 0.000 2.691; 0.000 1.000 0.000 2.000 0.000 2.522; 0.000 1.000 0.000 0.000 0.000 2.553; 0.000 1.000 0.000 2.000 0.000 2.702; 0.000 1.000 0.000 0.000 0.000 2.738; 0.000 1.000 0.000 0.000 0.000 2.789; 0.000 1.000 0.000 0.000 0.000 2.651;--------------------------------ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08--------------------------------Possible problem with experimental design:Check for duplicate entries and/or lack of range ofcontinuous variables within a class.If you seek help with this problem, make sure to send: 1. Your command line: mri_glmfit --y /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/y.mgh --fsgd /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/qdec.fsgd dods --glmdir /Applications/freesurfer/subjects/subject_prova/qdec/Untitled --surf fsaverage lh --label /Applications/freesurfer/subjects/subject_prova/fsaverage/label/lh.aparc.label --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-thickness-NPStest-Cor.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Cor-thickness-NPStest.mat 2. The FSGD file (if using one) 3. And the design matrix aboveError in Analyze: command failed: mri_glmfit --y /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/y.mgh --fsgd /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/qdec.fsgd dods --glmdir /Applications/freesurfer/subjects/subject_prova/qdec/Untitled --surf fsaverage lh --label /Applications/freesurfer/subjects/subject_prova/fsaverage/label/lh.aparc.label --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-thickness-NPStest-Cor.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Cor-thickness-NPStest.mat I don't understand what's happen? Thanks,

Stefano