Sample the voxel-wise data onto the surface. Then use the --pvr (per-vertex regressor) option in mri_glmfit. Search the mail archives for more info.

On 11/20/2018 04:23 AM, Carola Mayer wrote:

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Hello Freesurfer Developers,

I have a general question about how to analyse a certain combination of data. I have an independent variable that contains voxel-wise data and I have a dependent variable that contains vertex-wise cortical thickness values.

I would like to do a between-subjects analysis correlating the voxel-wise and vertex-wise data. What is a valid approach to do this? Should I first register the voxel-wise data onto the vertex-wise data and then register them into an average space to do group analysis? Or is a different method more valid?

Thanks in advance for your time and help,

Carola

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