Hi Dorit, I would probably run recon-all on the mni152, then map the atlas onto the surface of the mni (mri_vol2surf with --regheader), then create an annotation of the atlas using mris_seg2annot (run with --help for examples), then use mris_apply_reg to transfer the annot to your individual subjects or to fsaverage. Run with --help for examples

On 3/6/18 5:53 PM, Dorit Kliemann wrote:

Hi, I’m trying to get an atlas (Harvard/Oxford sub&cortical) into individual space via surface registration. Motivation is to replicate a finding in volume space (functional data) in a normal population with that atlas in a lesion data set where transformation to template volume space is not feasible.

I think I found a way described in principle for one region below but it seems clumsy with a lot of steps , so I’d like to check if there is a better/more accurate ways with less transforms?

Any feedback appreciated!

Thanks, Dorit

1. create a registration file from FSL-MNItemplate to Freesurfer space and fsaverage

bbregister --s fsaverage --mov MNI152_T1_1mm_brain.nii.gz --init-fsl --init-header --reg mni2fsaverage.dat --T1 --o mni2fsaverage.nii

2. warp atlas from FSL-MNI space onto surface of fsaverage

mri_vol2surf --mov HarvardOxford-cort-maxprob-thr25-1mm.nii.gz --reg mni2fsaverage.dat --projdist-max 0 1 .01 --interp nearest --hemi lh --out lh.atlas.mgh

3. writing label for id = 1

mri_cor2label --i lh.atlas.mgh --surf fsaverage lh --id 1 --l ./lh.1.atlas

4. move label from fsaverage onto individual subject space

mri_label2label --srclabel lh.1.atlas --srcsubject fsaverage --trglabel lh.1.atlas --trgsubject subject --regmethod surface --hemi lh

5. create voluem form label

mri_label2vol --label subject/label/lh.1.atlas --subject subject --hemi lh --identity --temp subject/mri/brain.mgz --o lh.1.atlas.volume.nii --proj frac 0 1 .01

6. fix wholes/border ribbon

mri_binarize --dilate 1 --erode 1 --i lh.1.atlas.volume.nii --o lh.1.atlas.volumebin.nii --min 1 mris_calc -o lh.1.atlas.volumebinfixed.nii lh.1.atlas.volumebin.nii mul subject/mri/lh.ribbon.mgz

7. bring from subject T1-FS space (1mm) into subject's functional space

bbregister --s subject --mov func.nii --init-fsl --init-header --reg anat2func_register.dat --bold

8. warp atlas image from individual subject anat space to subject bold space

mri_label2vol --seg lh.1.atlas.volumebinfixed.nii --temp func.nii --reg anat2func_register.dat --fillthresh .5 --o lh.atlas.func.nii

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