Hi Ezequiel,

Yes, this is supported by mri_label2label if you save the coordinates in a .label file with vox2ras=scanner in the header. These are simple text files; you can find examples in the label subfolder of a FreeSurfer-processed subject.

However, this currently only works for rigid or affine transforms, that is, LTA files. What kind of transform are you looking to apply?

Best wishes, Malte

________________________________________ From: Ezequiel Mikulan emikulan@yahoo.com Sent: Monday, June 22, 2026 07:40 To: freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] apply mri_synthmorph transform to a set of coordinates

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Hi, I would like to know whether it is possible to apply a transform estimated with mri_synthmorph to a set of coordinates (i have them in RAS space). These are SEEG electrode positions, and the transform maps between a subject’s native space and the MNI152 template.

If this is not currently supported, is this something that might be added in the future?

Thanks a lot for your tools.

Best,

Ezequiel