Freesurfer

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30089 discussions

the intensity VS the bias field
by bowang21＠mail.ustc.edu.cn 03 May '12

03 May '12

Dear all, I just want to know the difference between the intensity and the bias field.Is not the intensity indicated by the bias field? yours BOBO

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Comparing Cortical Thickness
by Jeff Sadino 03 May '12

03 May '12

Hello FreeSurfers, I want to compare cortical thickness differences between my two groups. Is this the correct pipeline? I ran make_average_subject on each group. To get the study thickness file in control space, I did this: mri_surf2surf --srcsubject study --srcsurfval study/surf/lh.thickness --trgsubject control --trgsurfval control/surf/study.thickness.mgh --hemi lh And then to calculate the differences, I used: mris_thickness_diff -out diff.mgh control/surf/pial control/surf/lh.thickness control/surf/pial control/surf/study.thickness.mgh. Is this the right way to do this? mris_thickness_diff says it should only be used on the same subject. mris_diff says it is still being tested. I also see mris_thickness_comparison. Which command is the best to use to get a thickness difference map? Thank you very much, Jeff Sadino

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osgm and correction for multiple comparisons
by Nicki Langer 03 May '12

03 May '12

Dear Freesurfer experts, I've calculated a I used the mri_glmfit for a one-sample group means (osgm) analysis: mri_glmfit --y Tatool_lh_thickness.15.mgh --fsgd FSGD.txt --glmdir Tatool_Thickness_LH.glmdir --surf average lh --osgm --cortex with following FSGD file: GroupDescriptorFile 1 Title Tatool working_memory_group_young MeasurementName external Tessellation surface PlotFile /Applications/freesurfer/subjects/average_tatool/stats/ glm_wm_young/Tatool_lh_thickness.15.mgh DesignMatFile X.mat dods DeMeanFlag -1 ReScaleFlag 0 ResidualFWHM 21.999092 LogY 0 Class working_memory_group_young Input 20969474.long.20969474_base working_memory_group_young Input 20969474_T2.long.20969474_base working_memory_group_young Input 23912784.long.23912784_base working_memory_group_young Input 23912784_T2.long.23912784_base working_memory_group_young Input 25579161.long.25579161_base working_memory_group_young Input 25579161_T2.long.25579161_base working_memory_group_young Input 25793236.long.25793236_base working_memory_group_young Input 25793236_T2.long.25793236_base working_memory_group_young Input 27363346.long.27363346_base working_memory_group_young Input 27363346_T2.long.27363346_base working_memory_group_young Input 29378587.long.29378587_base working_memory_group_young Input 29378587_T2.long.29378587_base working_memory_group_young Input 29572758.long.29572758_base working_memory_group_young Input 29572758_T2.long.29572758_base working_memory_group_young Input 41282970.long.41282970_base working_memory_group_young Input 41282970_T2.long.41282970_base working_memory_group_young Input 45220481.long.45220481_base working_memory_group_young Input 45220481_T2.long.45220481_base working_memory_group_young Input 49925500.long.49925500_base working_memory_group_young Input 49925500_T2.long.49925500_base working_memory_group_young Input 52695504.long.52695504_base working_memory_group_young Input 52695504_T2.long.52695504_base working_memory_group_young Input 56064196.long.56064196_base working_memory_group_young Input 56064196_T2.long.56064196_base working_memory_group_young Input 56403386.long.56403386_base working_memory_group_young Input 56403386_T2.long.56403386_base working_memory_group_young Input 60241875.long.60241875_base working_memory_group_young Input 60241875_T2.long.60241875_base working_memory_group_young Input 75765433.long.75765433_base working_memory_group_young Input 75765433_T2.long.75765433_base working_memory_group_young Input 76596439.long.76596439_base working_memory_group_young Input 76596439_T2.long.76596439_base working_memory_group_young Creator mri_glmfit SUBJECTS_DIR /Applications/freesurfer/subjects SynthSeed 1315181525 In a second step, I tried to correct for mulitple comparisons by using the glmfit_sim: mri_glmfit-sim --glmdir Tatool_Thickness_LH.glmdir --sim mc-z 5000 1.3 lh_mc-z.abs --sim-sign abs --overwrite But there was the following errormessage: ERROR: dimension mismatch between y and X. y has 16 inputs, X has 32 rows. Has anybody solved this problem before? (When I delete 16 rows of the FSGD file the simulation works, but then I don't trust the output anymore) Thanks for your help. Best, Nicolas Nicolas Langer MSc.UZH (lic. phil.) Division Neuropsychology Institute of Psychology University of Zurich Binzmuehlestrasse 14, 8050 Zurich, Switzerland 0041 44 635 73 96 (phone office) 0041 76 422 46 45 (phone mobile) 0041 44 635 74 09 (fax office) BIN 4.D.04 (office room number) n.langer(a)psychologie.uzh.ch (email) nicolas.langer[at]uzh.ch (email) http://www.psychologie.uzh.ch/neuropsy/ (website)

2 1

Freeview scripting
by Auer, Tibor 03 May '12

03 May '12

Hi, I am looking for an option to script freeview as I could tksurfer via TCL. I checked the command-line options, and there is a "-cmd Load freeview commands from a text file", but I could not find any documentation about the language/syntax/commands. Could someone tell me, where can I find a reference about it? Thanks, Auer, Tibor M.D. Ph.D. Biomedizinische NMR Forschungs GmbH am Max-Planck Institut für Biophysikalische Chemie Am Fassberg 11 37077 Göttingen Germany Phone/Work: +49-(0)551-201-1725 Phone/Home: +49-(0)551-387-0076 Mobile: +49-(0)176-8012-7921 Mail: tauer(a)mpibpc.mpg.de

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Vertex correspondence between brains
by "Thomas W. Mühleisen" 03 May '12

03 May '12

Dear all, We have processed two individual datasets using the whole pipeline. We have recognized that the absolute number of generated vertices differs between the two brains (130k per hemisphere vs. 155k per hemisphere). Our question is how do the vertices from one brain correspond to those from the other brain? What happens to the 25k vertices which differ between both brains? Many thanks in advance for your answer! Best Regards, Thomas -- Dr. rer. nat. Thomas W. Muehleisen Postdoctoral Scientist Institute of Human Genetics Department of Genomics Life & Brain Center University of Bonn Sigmund-Freud-Strasse 25 D-53127 Bonn Germany Phone: +49 (0)228 6885 434 Cell phone: +49 (0)176 57001211 Fax: +49 (0)228 6885 401 Email: thomas.muehleisen(a)uni-bonn.de

2 1

Freeview-FSL
by Auer, Tibor 03 May '12

03 May '12

Hi, a bit connecting to my previous mail: How can I overlay an FSL activation map onto the surface in FreeView? The solution working in tksurfer (i.e. overlay) is not working here. I can load the data as a volume, but then it is not projected to the surface. Thanks, Auer, Tibor M.D. Ph.D. Biomedizinische NMR Forschungs GmbH am Max-Planck Institut für Biophysikalische Chemie Am Fassberg 11 37077 Göttingen Germany Phone/Work: +49-(0)551-201-1725 Phone/Home: +49-(0)551-387-0076 Mobile: +49-(0)176-8012-7921 Mail: tauer(a)mpibpc.mpg.de

1 0

OBJ conversion
by Darshan P 03 May '12

03 May '12

Hello all, I was wondering if I can convert the surface outputs to an OBJ mesh file format . Since most of the applications are in windows I was hoping if there is conversion tool to do this . Regards Darshan

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Question about version upgrade
by Efrat Kliper 02 May '12

02 May '12

Dear FreeSurfer expert, I am currently working on FreeSurfer Version 4.5.0 and already performed an analysis for approximately 200 subjects. Is there a way to change the version that I am working on (4.5.0) to 5.0.1 without the need to run recon-all again in the new version? Thanks in advanced, efrat

5 5

correlation coefficient
by Tetiana Dadakova 02 May '12

02 May '12

Dear FS experts, I try to look at correlation between thickness and performance. I run mri_glmfit (using performance as covariate) and mri_glmfit-sim. After this I get some significant clusters. I would like to ask if I could get a correlation coefficient for these clusters, or/and a regression plot? Thank you, Tanja.

2 1

How to obtain cortical thickness in fsaverage space
by ZhiLiangLong 02 May '12

02 May '12

Hi all: After finishing group analysis, how can i obtain the thickness value of each ROIs showing significant group-difference in fsaverage space? That is to say, how i get the value of each ROIs which have been normalized to the fsaverage template. The method suggested in tutorials page(http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/QdecGroupAnalysis) just tells the way to get the thickness values in individual space.

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