Hi, To be specific, I'm trying to reconstruct arcuate fasciculus (refer to SLFT according to your paper 2011) in patients who suffered from frontal or temporal or parietal gliomas. I noticed that TRACULA was used to study neuropsychiatry and neurodegeneration diseases, such as schizophrenia, autism etc. When it comes to organic diseases, like brain tumor, white matter structures may be pushed or deformed due to mass effect. So my question is should I involve the patients in the training set? What can I do to succeed in reconstruction of arcuate fasciculus using TRACULA in my research? Thanks for your time. BW, yang
------------------ Original ------------------ From: "ayendiki";ayendiki@nmr.mgh.harvard.edu; Date: Jun 2, 2016 To: "Freesurfer support list"freesurfer@nmr.mgh.harvard.edu;
Subject: Re: [Freesurfer] About TRACULA
Hi - It's hard to predict in advance what will happen without trying it out. A lot will depend on the size/position/nature of the tumor. Some tumor patients will go through just fine, other will have issues. If the freesurfer segmentation works, then tracula will work too.
Best, a.y
On Thu, 2 Jun 2016, yangfuxing wrote:
Dear professor, I'm a postgraduate of neurosurgery. Recently, I'm interested in cortical parcellation and subcortical segmentation using freesurfer. In my study, all patients have brain tumors. So I begin to wonder if "recon-all" can still be applied to these subjects, or in other word, is it possible that freesurfer's automated brain segmentation could be applied to brain tumor patients because their normal structures were changed? If I just run it regularly according to fswiki, would the outcome be accurate? Second question is about automatic tractography using TRACULA. Similarly, I'd like to use "trac-all" to reconstruct arcuate fasciculus in patients with brain tumor, is it possible? How can I set up the configuration? Hope to hear from you soon. Best wishes! Sincerely
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