Thank you very much again Dough, I was hoping that i understood how to make a contrast!
Thank you! To: freesurfer@nmr.mgh.harvard.edu From: greve@nmr.mgh.harvard.edu Date: Thu, 9 Jun 2016 22:10:04 -0400 Subject: Re: [Freesurfer] contrast
I responded in the body of the email
On 6/9/16 7:57 PM, Dave Yas wrote:
Helllo!
That was an empty email!
> To: freesurfer@nmr.mgh.harvard.edu
> From: greve@nmr.mgh.harvard.edu
> Date: Thu, 9 Jun 2016 16:33:48 -0400
> Subject: Re: [Freesurfer] contrast
>
>
>
> On 06/08/2016 11:40 PM, Dave Yas wrote:
> > Thank you very much Dough!
> >
> > I need to check 4 contrasts. I made them based on the freesurfer page,
> > but cant decide if i interpreted them right!
> > Are my contrasts Ok?
> >
> > If classes are:
> > Patients, healthy control
> >
> > and variables are:
> > Age, TIV, father age, mother age.
> >
> > Are these contrasts ok?
> >
> > R# = 2* (4+1) = 10
> >
> > *contrast1:* 0 0 0 0 0 0 -1 1 -1 1>> checking the differences between
> > groups in terms of father and mother age regression out the effect of
> > age and TIV
> That will effectively compute the difference between the mean(father
> age + mother age), ie, it would be like analyzing with a regressor
> created by adding the father age and mother age (ie, mean parent age).
> Is that what you want?
> >
> > *contrast2:* 0 0 0 0 0 0 -1 1 0 0
> > 0 0 0 0 0 0 0 0 1 -1 >> checking the differences
> > between groups in terms of father or mother age regression out the
> > effect of age and TIV
> This will be significant if either the father age is diff OR the mother
> age is diff (or some combination thereof). It will be similar to
> contrast1 but not identical.
> >
> > *contrast3:* 0 0 0 0 0 0 -1 1 0 0 >> checking the differences between
> > groups in terms of father age regression out the effect of age and TIV
> > and mother age
> Yes
> >
> > *contrast4: *0 0 0 0 0 0 0 0 -1 1 >> checking the differences between
> > groups in terms of mother age regression out the effect of age and TIV
> > and father age
> Yes
> >
> > Yas
> >
> >
> >
> > ------------------------------------------------------------------------
> > To: freesurfer@nmr.mgh.harvard.edu
> > From: greve@nmr.mgh.harvard.edu
> > Date: Wed, 8 Jun 2016 09:38:18 -0400
> > Subject: Re: [Freesurfer] Coordinate system in mris_convert
> >
> >
> > Try the group analysis tutorial
> > http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis
> >
> > On 6/8/16 2:39 AM, Dave Yas wrote:
> >
> > Hello all,
> >
> > I'm new to surface analysis.
> >
> > I have 2 groups (patient and healthy control) that i want to check
> > differences between.
> > I want to perform cortical thickness/ surface analysis.
> > My categories are
> > Patients, healthy control, age, TIV, father age, mother age.
> > Where age & TIV are covariates of no interest. and father and
> > mother age are covariates of interest.
> >
> > I have already preprocessed the data (recon-all), but how can i
> > proceed?
> > Any online guide on steps for surface analysis? also making a
> > design such as the above?
> >
> > Yas
> >
> >
> >
> > _______________________________________________
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> >
> >
> >
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> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> greve@nmr.mgh.harvard.edu
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>
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The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.