Hi Mudathir,
The two templates were created by using the same 40 subjects as a training data set as is used by Freesurfer. The volumes were registered to a common space by an iterative framework in which you create a mean, register individuals to it and then re-create the mean. We then reconned the final mean. The MNI equivalent was created by moving the mean to the MNI152 space before running recon.
The above explains why those 40 subjects were used for the template.
Best, Lilla ________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu on behalf of バキット・ムダシル m-bakhit@fmu.ac.jp Sent: Wednesday, April 14, 2021 6:55 AM To: Freesurfer support list Freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] The cvs_avg35
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Hi, I was looking for any document describes how the cvs_avg35 and cvs_avg35_inMNI152 were made? Can you please send me a link or give me a brief about it please? I searched in the freesurfer wiki and here in the freesurfer folder but no success. Also, I found from literature that the fsaverage was made from a data of 40 subjects that includes 10 cases of Alzheimer disease. Can I ask what was the reason to include those 10 cases to create this template?
Thanks
Mudathir
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