I responded in the body of the email
On 6/9/16 7:57 PM, Dave Yas wrote:
/*Helllo!
That was an empty email! */
To: freesurfer@nmr.mgh.harvard.edu From: greve@nmr.mgh.harvard.edu Date: Thu, 9 Jun 2016 16:33:48 -0400 Subject: Re: [Freesurfer] contrast
On 06/08/2016 11:40 PM, Dave Yas wrote:
Thank you very much Dough!
I need to check 4 contrasts. I made them based on the freesurfer
page,
but cant decide if i interpreted them right! Are my contrasts Ok?
If classes are: Patients, healthy control
and variables are: Age, TIV, father age, mother age.
Are these contrasts ok?
R# = 2* (4+1) = 10
*contrast1:* 0 0 0 0 0 0 -1 1 -1 1>> checking the differences between groups in terms of father and mother age regression out the effect of age and TIV
That will effectively compute the difference between the mean(father age + mother age), ie, it would be like analyzing with a regressor created by adding the father age and mother age (ie, mean parent age). Is that what you want?
*contrast2:* 0 0 0 0 0 0 -1 1 0 0 0 0 0 0 0 0 0 0 1 -1 >> checking the differences between groups in terms of father or mother age regression out the effect of age and TIV
This will be significant if either the father age is diff OR the mother age is diff (or some combination thereof). It will be similar to contrast1 but not identical.
*contrast3:* 0 0 0 0 0 0 -1 1 0 0 >> checking the differences between groups in terms of father age regression out the effect of age and
TIV
and mother age
Yes
*contrast4: *0 0 0 0 0 0 0 0 -1 1 >> checking the differences between groups in terms of mother age regression out the effect of age and
TIV
and father age
Yes
Yas
To: freesurfer@nmr.mgh.harvard.edu From: greve@nmr.mgh.harvard.edu Date: Wed, 8 Jun 2016 09:38:18 -0400 Subject: Re: [Freesurfer] Coordinate system in mris_convert
Try the group analysis tutorial http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis
On 6/8/16 2:39 AM, Dave Yas wrote:
Hello all,
I'm new to surface analysis.
I have 2 groups (patient and healthy control) that i want to check differences between. I want to perform cortical thickness/ surface analysis. My categories are Patients, healthy control, age, TIV, father age, mother age. Where age & TIV are covariates of no interest. and father and mother age are covariates of interest.
I have already preprocessed the data (recon-all), but how can i proceed? Any online guide on steps for surface analysis? also making a design such as the above?
Yas
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