Sorry, what is "pc1"?
On 1/14/2020 9:44 AM, Swati Rane wrote:
External Email - Use Caution Hello,
I was wondering if someone could answer my question below
Can I use mri_glmfit-sim after mri_glmfit on the longitudinal pc1 files.
Are there any set of parameters that should be set differently when using pc1 instead of thickness files?
Thanks! Swati
____________________________________________ Swati Rane Levendovszky, PhD Interim Director,Diagnostic Imaging Sciences Center Assistant Professor,Integrated Brain Imaging Center Radiology University of Washington Box 357115 | AA035 HSB | Seattle, WA 98195 srleven@uw.edumailto:srleven@uw.edu | Ph: 206 543 6159 Web: https://sites.google.com/site/uwswatirane/ ____________________________________________
From: freesurfer-bounces@nmr.mgh.harvard.edumailto:freesurfer-bounces@nmr.mgh.harvard.edu on behalf of Swati Rane srleven@uw.edumailto:srleven@uw.edu Reply-To: Freesurfer support list freesurfer@nmr.mgh.harvard.edumailto:freesurfer@nmr.mgh.harvard.edu Date: Friday, January 10, 2020 at 10:06 AM To: "freesurfer@nmr.mgh.harvard.edu"mailto:freesurfer@nmr.mgh.harvard.edu freesurfer@nmr.mgh.harvard.edumailto:freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] mri_glmfit-sim for longitudinal pipelines
External Email - Use Caution Hello FreeSurfer Developers,
I'm attempting to compare longitudinal cortical thinning rates (pc1) between 3 groups using mri_glmfit using FreeSurfer 6.0. The tutorial suggests that you could use the multiple comparisons corrections that come with it but does not comment on using the mri_glmfit-sim option.
I just want to confirm whether there is anything prohibiting me from using mri_glmfit-sim. Are there any set of parameters that should be set differently when using pc-1 instead of thickness files?
Also, would you do a stricter correction and stick to the longitudinal model or prefer the linear mixed effects model and do a FDR? How do you decide between the two?
Thanks! Swati
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