sorry, I'm not sure I'm following. It looks like you did two analyses, one with 10mm smoothing and CFT=.05, the other with 12mm and CFT=.001. You get a cluster for each in the same area, but they are not overlapping. Is that right?
On 1/6/2020 2:58 PM, Martin Juneja wrote:
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Hi,
I am using Monte-Carlo simulations (for cortical thickness and volume - behavioral analysis) for clusterwise correction for multiple comparisons.
My results are either significant at (i) CFT < 0.001 and CWT < 0.1 (i.e., CWT = 0.07) (smoothing 12 mm) for cortical thickness-behavior analysis - with maxima at -4.3 (CFT) or (ii) CFT < 0.05 and CWT < 0.001 (i.e., CWT = 0.0002) (smoothing 10 mm) for cortical volume-behavior - with maxima at -4.53 (CFT)
Both the clusters in (i) (lateral orbital frontal) and (ii) (rostral middle) are within the frontal cortex, but not overlapping ! Also, although maxima is at (i) -4.3 and (ii) -4.53, still the clusters do not survive recommended thresholds suggested in https://www.ncbi.nlm.nih.gov/pubmed/29288131 And the FPR in this paper at strong CWT (i..e, 0.001) and liberal CFT (i..e, 0.05) is not calculated.
So I was wondering if there is any recommendation from the experts regarding these results, or none of these make sense because I never get CFT < 0.001 and CWT < 0.05 (at-least).
Any help would be really appreciated.
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