maybe the fimbria/alveus is different on the left than the right? Not sure, but if the protocols are different it's very difficult to make any meaningful comparison Bruce On Tue, 2 Oct 2012, Ana Arruda wrote:
That fact can explain the differences between manual and automatic segmentations. But how can I explain the differences just for the left-hippocampus values in Freesurfer? Comparing percent volume difference between Freesurfer-Manual and FSL-Manual, the percent is bigger in left-hippocampus for Freesurfer-Manual. And according to the literature (Morey et al.) the percent volume difference for Freesurfer-Manual is always smaller than FSL-Manual as you can see in Fig. 5 of that article.
FSL Manual Freesurfer HD HE HD HE HD HE 3810.741698 3382.601803 3355.5 3007.5 3705 3721 3409.829467 2860.187224 2868 2653.5 3382 3331 3306.409891 3381.885156 3025.5 3001.5 3358 3575 3794.767147 2907.559116 2880 2769 3651 3474 4521.450897 4587.515346 3642 3468 4049 4113 3794.638317 3841.111348 3042 3066 4061 4242
4772.512671 4028.949924 3570 3496.5 4812 4801 4025.037115 3833.11259 3772.5 3513 4094 4224 ? ? 3196.5 2704.5 ? ? 2900.838938 2705.713765 2526 2466 3184 2820 3607.996048 3061.21013 2749.5 2589 3852 3591 3694.401205 3343.946802 2682 2559 3530 3507 4562.195757 4484.215251 3156 3286.5 4114 4599