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Today's Topics:
1. Re: Displaying significant difference with a threshold of
cluster size (Douglas N Greve)
2. Re: Displaying significant difference with a threshold of
cluster size (liang wang)
3. Troubleshooting: Are these pial and wm surface acceptable?
(xuemei lei)
----------------------------------------------------------------------
Message: 1
Date: Sun, 11 Jul 2010 13:42:39 -0400
From: Douglas N Greve greve@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Displaying significant difference with a
threshold of cluster size
To: liang wang wanglbit@gmail.com
Cc: freesurfer@nmr.mgh.harvard.edu
Message-ID: 4C3A028F.7070800@nmr.mgh.harvard.edu
Content-Type: text/plain; charset=ISO-8859-1; format=flowed
You should correct for multiple comparisons using cluster-wise
correction. See the tutorials on group analysis on our wiki.
doug
liang wang wrote:
Hi,
Using mri_glmfit, I found significant between-group difference in
cortical thickness in some regions. However, there are a lot regions
with very small vertices surviving the given threshold. What I need to
do is displaying large clusters (e.g. having 20 vertices at least)
assumed as "true" difference. I don't know how to make it by a
selected threshold of cluster size . Any suggestions would be appreciated.
Liang
--
Liang Wang, PhD
Postdoctoral Fellow
Woodward Lab
Department of Psychiatry
University of British Columbia
BC Mental Health & Addiction Services
938 West 28th Avenue
Vancouver BC V5Z 4H4
Telephone: 1-604-875-2000 (ext. 4735)
Fax: 1-604-875-3871
Email: wanglbit@gmail.com mailto:wanglbit@gmail.com
Freesurfer mailing list
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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
------------------------------
Message: 2
Date: Sun, 11 Jul 2010 11:16:17 -0700
From: liang wang
wanglbit@gmail.com
Subject: Re: [Freesurfer] Displaying significant difference with a
threshold of cluster size
To: freesurfer@nmr.mgh.harvard.edu
Message-ID:
AANLkTinU0knZdFiivSrtnnF4LuV_SlK5iH7eftriOV1-@mail.gmail.com
Content-Type: text/plain; charset="iso-8859-1"
Hello Doug,
Thanks for your kind response. I have tried to use mri_glmfit-sim to correct
the results. However, no significant differences were observed. To compare
with other studies, I would like to report the results (p < 0.001,
uncorrected) and mention that they will disappear if corrected by
cluster-based threshold method. Is it a acceptable way?
Liang
2010/7/11 Douglas N Greve
greve@nmr.mgh.harvard.edu
> You should correct for multiple comparisons using cluster-wise correction.
> See the tutorials on group analysis on our wiki.
>
> doug
>
> liang wang wrote:
>
>> Hi,
>>
>> Using mri_glmfit, I found significant between-group difference in cortical
>> thickness in some regions. However, there are a lot regions with very small
>> vertices surviving the given threshold. What I need to do is displaying
>> large clusters (e.g. having 20 vertices at least) assumed as "true"
>> difference. I don't know how to make it by a selected threshold of cluster
>> size . Any suggestions would be appreciated.
>>
>> Liang
>>
>> --
>> Liang Wang, PhD
>> Postdoctoral Fellow
>> Woodward Lab
>> Department of Psychiatry
>> University of British Columbia
>> BC Mental Health & Addiction Services
>> 938 West 28th Avenue
>> Vancouver BC V5Z 4H4
>> Telephone: 1-604-875-2000 (ext. 4735)
>> Fax: 1-604-875-3871
>> Email: wanglbit@gmail.com
mailto:wanglbit@gmail.com
>> ------------------------------------------------------------------------
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>>
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> greve@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358 Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>
>
--
Liang Wang, PhD
Postdoctoral Fellow
Woodward Lab
Department of Psychiatry
University of British Columbia
BC Mental Health & Addiction Services
938 West 28th Avenue
Vancouver BC V5Z 4H4
Telephone: 1-604-875-2000 (ext. 4735)
Fax: 1-604-875-3871
Email: wanglbit@gmail.com
