I'm curious about the use of this method as well (thanks for the paper PPJ). Bruce/Doug, how exactly does QDEC treat this design? Can a single-subject comparison properly be done? Thanks.
-Derin
On Mar 23, 2011, at 4:11 PM, Pedro Paulo de Magalhães Oliveira Junior wrote:
We have dono something like this in Cortical thickness reduction of normal appearing cortex in patients with polymicrogyria
cheers,
PPJ
Pedro Paulo de Magalhães Oliveira Junior Diretor de Operações Netfilter & SpeedComm Telecom -- www.netfilter.com.br -- For mobile: http://www.netfilter.com.br/mobile
On Wed, Mar 23, 2011 at 14:21, Emily Rogalski erogalski@gmail.com wrote: Using q dec we have run a single patient versus a group of healthy control subjects (n=20ish) and found significant differences even after FDR correction.
Could you describe the process qdec uses to compute these differences? Is it legitimate to report these single subject maps? Practically this is very useful for case reports but Im concerned about violating statistical rules.
Thanks!
Emily J Rogalski, PhD Assistant Research Professor Northwestern University Cognitive Neurology and Alzheimer's Disease Center (CNADC) 320 E Superior Street Searle Building 11th Floor Chicago, IL 60611 312-503-1155 phone 312-908-8789 fax erogalski@gmail.com
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