Hello, Freesurfer experts:
We are extracting the average cortical thickness of each hemisphere for every subject using mris_anatomical_stats. We found that for one subject (attached below), the thickness measures are quite similar but the “intrinsic curvature index” differs drastically between left/right hemispheres. Will this curvature index affect the validity of our thickness measure?
Thanks in advance
Karl
***the left hemisphere
mris_anatomical_stats -l lh.cortex.label -f subject1l.txt subject1 lh
limiting computations to label lh.cortex.label.
reading volume /usr/local/freesurfer/subjects/subject1/mri/wm.mgz...
reading input surface /usr/local/freesurfer/subjects/subject1/surf/lh.white...
reading input pial surface /usr/local/freesurfer/subjects/subject1/surf/lh.pial...
reading input white surface /usr/local/freesurfer/subjects/subject1/surf/lh.white...
structure is "lh.cortex.label"
number of vertices = 157421
total surface area = 102165 mm^2
total gray matter volume = 290073 mm^3
average cortical thickness = 2.488 mm +- 0.694 mm
average integrated rectified mean curvature = 0.170
average integrated rectified Gaussian curvature = 0.105
folding index = 4980
intrinsic curvature index = 592.3
***the right hemisphere
mris_anatomical_stats -l rh.cortex.label -f subject1r.txt subject1 rh
limiting computations to label rh.cortex.label.
reading volume /usr/local/freesurfer/subjects/subject1/mri/wm.mgz...
reading input surface /usr/local/freesurfer/subjects/subject1/surf/rh.white...
reading input pial surface /usr/local/freesurfer/subjects/subject1/surf/rh.pial...
reading input white surface /usr/local/freesurfer/subjects/subject1/surf/rh.white...
structure is "rh.cortex.label"
number of vertices = 158401
total surface area = 102285 mm^2
total gray matter volume = 291519 mm^3
average cortical thickness = 2.482 mm +- 0.707 mm
average integrated rectified mean curvature = 0.173
average integrated rectified Gaussian curvature = 0.299
folding index = 5756