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Dear Freesurfer team,
When I analyse the mean curvature value of a particular ROI, do I have to control for overall brain curvature, to make sure the results are not driven by individual differences in overall brain curvature?
Best wishes,
Letitia Schneider
Hi Letitia
I wouldn't think so since mean curvature is a differential property and so should be pretty local, but I guess controlling for overall curvature would be a slightly different hypothesis
Cheers Bruce
From: freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu On Behalf Of Letitia Schneider Sent: Friday, November 27, 2020 8:56 AM To: freesurfer@nmr.mgh.harvard.edu Cc: Josue Luiz Dalboni Da Rocha Josue.Dalboni@unige.ch Subject: [Freesurfer] Mean Curvature
External Email - Use Caution
Dear Freesurfer team,
When I analyse the mean curvature value of a particular ROI, do I have to control for overall brain curvature, to make sure the results are not driven by individual differences in overall brain curvature?
Best wishes,
Letitia Schneider
I don't know. I've never seen this type of analysis. I think with and without would be valid analyses, but they would be answering different questions, so, as the scientist doing the study, it is more up to you.
On 11/27/2020 8:56 AM, Letitia Schneider wrote:
freesurfer@nmr.mgh.harvard.edu
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Fischl, Bruce -
Greve, Douglas N.,Ph.D. -
Letitia Schneider