Hi,
To run bbregister outside of the recon stream, I tried:
setenv SUBJECTS_DIR /autofs/space/brownie_003/users/gcoombs/SUBJECTS_DIR
cd $SUBJECTS_DIR
bbregister --mov mri/nu.mgz --int ../mni305.cor.mgz --reg mri/transforms/talairachTEST.xfm --init-spm --t1 --s amac_TEST --tmp ./TEMP
but when I tried to view it with:
tkregister2 --mov amac_TEST/mri/nu.mgz --fstal --reg amac_TEST/mri/transforms/talairachTEST.xfm --surf orig --s amac_TEST
It looks the same as it did before, and I am concerned that the bad tal registration will affect the localization of fMRI data and ICV measurements. Does anyone have any advice on how to fix the registration?
Thanks,
Garth
>
> --
>
> On Tue, 16 Mar 2010, Garth Coombs wrote:
>
>> Hi,
>>
>> I recently ran into a problem with some of my tal registrations during the recon-all process (see below message to Martino's Tech). In order to fix the problem, it was suggested that we run bbregister outside of the recon-all stream and then feed that registration into the subsequent recon stages. Does this make sense, and how would I go about doing this? I'm not sure what the --mov file should be, or if there is a way to specify fstal as the reference structural.
>>
>> Thanks for your help!
>>
>> -Garth
>>
>> Hi Doug & FreeSurfers,
>>
>> I recently re-ran a large number of recons and have been checking to make sure
>> they all ran correctly, and I have come up with a couple of questions about the
>> talairach transform/recon checking.
>>
>> For some of my recons, the green line outlining the white matter on the
>> individual brain extends slightly further than the cortex surface of the fstal
>> brain. While it looks relatively well aligned (e.g. ventricles, brain stem), the
>> fstal brain looks slightly too small for the subject's brain. Additionally, the
>> green outline tends to extend into the skull of fstal in the sagittal plane. An
>> example is:
>>
>> setenv SUBJECTS_DIR /autofs/space/brownie_003/users/gcoombs/SUBJECTS_DIR/
>> tkregister2 --mgz --fstal --surf orig --s amac_anat
>>
>> or
>>
>> tkregister2 --mgz --fstal --surf orig --s amra_anat
>>
>> In order to fix these talairach transforms, it seems like the best option would
>> be to scale the brain; however, we will be doing a cortical thickness analysis
>> on this group, and we do not want to scale the brain if it will somehow affect
>> the outcomes. Is this something we should worry about?
>>
>> Another question we have is about general recon quality control: when checking
>> that the recons ran smoothly, what should we look for? I look to make sure that
>> the pial and white matter surface lines don't include dura or any other matter
>> and that they follow the structures correctly, skull stripping, and intensity
>> normalization, but is there anything else that is particularly important?
>>
>> Any advice would be greatly appreciated!
>>
>> Thanks,
>> Garth
>>
>
>