I am editing a paper on subcortical volumes in deficit schizophrenia after
some reviewers' comments.
On of them suggested me to correct the volumes of subcortical structures
for whole brain volume instead of intracranial volume. In the reviewer's
opinion ICV estimated by FreeSurfer 5.1 has a bad quality and is not
reliable. However, neither the reviewer provides any evidence, nor I could
find any...
Is there any evidence for this?
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Pietro De Rossi, MD
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Sapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento
NESMOS (Neuroscienze, Salute Mentale, Organi di Senso), Ospedale
Sant'Andrea, Via di Grottarossa 1035-1039, 00189 Roma
NESMOS Department (Neurosciences, Mental Health and Sensory Functions),
School of Medicine and Psychology, Sapienza University, Sant’Andrea
Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy
Laboratorio di Neuropsichiatria, Dipartimento di Neurologia Clinica e
Comportamentale, IRCCS Fondazione Santa Lucia, via Ardeatina 306 - 00179
Roma
Tel. +39 (0)6 51501358
Fax +39 (0)6 90280774
web:
http://www.neuropsichiatrialab.com